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KMID : 0614620160670050272
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Korean Journal of Gastroenterology
2016 Volume.67 No. 5 p.272 ~ p.276
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Repeated Panniculitis Induced by Pegylated Interferon Alpha 2a in a Patient with Chronic Hepatitis C
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Song Jun-Seok
Sohn Joo-Hyun
Jeong Jae-Yoon
Min Ji-Hee
Choi Won-Seok
Kim Oon-Zoong
Pyo Ju-Yeon
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Abstract
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Pegylated interferon alpha (PEG-IFN-α) is widely used to treat chronic hepatitis C in combination with ribavirin. Many adverse effects of PEG-IFN-α, such as hematologic, psychologic, dermatologic, immunologic, and other abnormalities, have been reported, and some serious adverse events lead to PEG-IFN-α treatment discontinuation. For very rare adverse events such as panniculitis, there are no established guidelines on whether to continue PEG-IFN-α treatment. Published reports on panniculitis induced by PEG-IFN-α 2a are sparse. Herein we report a case of repeated occurrences of panniculitis in a patient with chronic hepatitis C, leading to treatment cessation.
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KEYWORD
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Panniculitis, Peginterferon alfa-2a, Hepatitis C, Adverse effects
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